Comparative study of different diagnostic methods for detection of mycobacteria in clinically suspected patients of extrapulmonary tuberculosis at IGIMS, Patna

Background: Tuberculosis is a global problem and incidence of extra pulmonary tuberculosis increasing day by day. Diagnosis little bit difficult than tuberculosis. Aim Objective: The aim this study to compare different diagnostic methods like ZN staining, LED-FM GeneXpert assay for detection Mycobacterium in extrapulmonary (EPTB) cases respect their sensitivity, specificity, PPV NPV respectively. Methodology: This prospective was carried out the Department Microbiology, IGIMS, Patna, Bihar. Samples from 210 suspected were collected processed ZN-stain, LED-FM, MGIT culture. Taking culture result as Gold standard, compared. Result: Out samples, rate 10.47%, 14.28 %, 30.47% 36.66% staining 28.27 100%, 70.74% 39.96%, 73.88% 59.74%, 86.46%, 71.87% 78.76%